Esomeprazole combined with mosapride therapy for 90 cases of reflux esophagitis

Objective To study the effect of esomeprazole and mosapride on treatment of reflux esophagitis (RE). Methods 90 RE patients were randomly divided into two groups,the treatment group (45 cases):5 mg of mosapride tid,20 mg of esomeprazole qd were taken orally; the control group (45 cases):20 mg esomeprazole qd were taken orally. The symptoms were evaluated from pretreatment to every two weeks after the treatment. The endoscope findings at the end of 6 weeks were recheched. Results The clinical curative rates were 100% in the treatment group and 86. 7% in the control group,the efficient rate evaluation under endoscope were 97. 8% ,84. 4% respectively. There was significant difference between the two groups ( P 0. 05). Conclusion The effect of esomeprazole combined with mosapride on treating the reflux esophagitis was obviously superior to the other group.