Valuation of curative effect on reflux esophagitis treated by mosapride combined with someprazole

Objective To observe the effect of the mosapride combined with esomeprazole against the reflux esophagitis.Methods To divide the reflux esophagitis patients confirmed with endoscope into the control group and the treatment group.The treatment group included 40 patients and the control group included 40 patients.The treatment group was treated with the esomeprazole 40 mg,once a day;mosapride 5 mg,3 times a day,the control group was treated with the omeprazole 20 mg,once a day;mosapride 5 mg,3 times a day,two groups lasted 4,8 weeks.The effects were evaluated with symptoms and gastroscop when on fourth week and eighth week.Results The clinical curative rates were 97.5% in the treatment group and 80% in the control group.The efficient rate evaluation under endoscope were 95% in the treatment group and 75% in the control group when on eighth week.There was significant difference between the two groups(P0.05).Conclusion Esomeprazole combined with mosapride is effective to reflux esophagitis and is worth to use widely in clinical treatment.