ScholarLens Back to search
2004•Journal of Zhengzhou UniversityRequires access

Influence of defibrase on the cerebral infaction volume of brain ischemia reperfusion in rats

Rong Bai

Open publisher page 0 citations

Abstract

Aim: To observe the influence of defibrase on the cerebral infaction volume of brain ischemia reperfusion in rats. Methods: Using the model of rat ischemra reperfusion, the influence of the cerebral infaction volume at various time points after defibrase treatment were observed. Results: The infaction volume significantly decreaced in fibrinolytic groups when reperfusing 6 h and 24 h after ischemra 3 h compared with the saline control group.While there was no significant difference between the defibrase groups and the saline control group when reperfusion 3 h after ischemra 3 h and reperfusion 3 h,6 h and 24 h after ischemia 6 h . Conclusion: The defibrase can decreace the cerebral ischemra volume, expend therapeutic window of brain infarction and have protective effect on the brain tissue.

About this research paper

What this paper is about

Aim: To observe the influence of defibrase on the cerebral infaction volume of brain ischemia reperfusion in rats. Methods: Using the model of rat ischemra reperfusion, the influence of the cerebral infaction volume at various time points after defibrase treatment were observed. Results: The infaction volume significantly decreaced in fibrinolytic groups when reperfusing 6 h and 24 h after ischemra 3 h compared with the saline control group.While there was no significant difference between the defibrase groups and the saline control group when reperfusion 3 h after ischemra 3 h and reperfusion 3 h,6 h and 24 h after ischemia 6 h . Conclusion: The defibrase can decreace the cerebral ischemra volume, expend therapeutic window of brain infarction and have protective effect on the brain tissue.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Aim: To observe the influence of defibrase on the cerebral infaction volume of brain ischemia reperfusion in rats. Methods: Using the model of rat ischemra reperfusion, the influence of the cerebral infaction volume at various time points after defibrase treatment were observed. Results: The infaction volume significantly decreaced in fibrinolytic groups when reperfusing 6 h and 24 h after ischemra 3 h compared with the saline control group.While there was no significant difference between the defibrase groups and the saline control group when reperfusion 3 h after ischemra 3 h and reperfusion 3 h,6 h and 24 h after ischemia 6 h . Conclusion: The defibrase can decreace the cerebral ischemra volume, expend therapeutic window of brain infarction and have protective effect on the brain tissue.

Key concepts: Ischemia, Saline, Medicine, Reperfusion injury, Brain infarction, Anesthesia, Cerebral infarction, Volume (thermodynamics)

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Influence of defibrase on the cerebral infaction volume of brain ischemia reperfusion in rats — Research Paper | ScholarLens