The Clinical Effect of Intermittent and Continuous Hemoperfusion in the Treatment of Acute Paraquat Poisoning

Objective:To assess the clinical effects of intermittent and continuous hemoperfusion on acute paraquat poisoning.Method:59 patients with acute paraquat poisoning were randomly divided into two groups,A group composed of 26 patients were treated with intermittent hemoperfusion and continuous hemoperfusion was administered in B group composed of 33 patients.All patients were treated with conventional medication.then,According to the prognosis of the patients was divided into death group and survival group.Result:There were no significant difference in Gender,age,the toxic dose,and after the poisoning to hospitalization time between the two groups(P0.05).Therapeutic effect of the A and B group had no difference(P0.05).The survival time of death patients in the B group was longer than that of death patients in the A group(P0.05).Compared with the survival group,the toxic dose was higher significantly in death group.Conclusion:There is no difference in the clinical efficacy between intermittent and continuous hemoperfusion on acute paraquat poisoning,continuous hemoperfusion can prolong the survival time of death obviously,the main causes of death is related to the toxic dose.