Application of syphilis serology test in diagnosis of syphilis
Xiong ChunLian, Fangcai Li, Zhan Xiaomei, Heping Su, Lili Chen
Abstract
Xiong ChunLian, Fangcai Li, Zhan Xiaomei, Heping Su, Lili Chen
Abstract
OBJECTIVE To evaluate the three kinds of syphilis serologic test in the diagnosis of syphilis in the application.METHODS A total of 65 cases of syphilis positive sera and 96 healthy individuals negative sera were detected by TPHA,TP-ELISA,and the TPPA three methods.RESULTS TRUST was used to detecte 65 cases of syphilis in serum,61 cases of positive and negative in 4 cases,the positive rate of 93.8%.TP-ELISA detected out 65 cases of syphilis in serum,63 cases of positive and negative in 2 cases,positive rate of 96.9%.TPPT detected 65 cases of syphilis,65 cases of positive and negative 0 cases,the positive rate of 100%.Three methods tested 96 cases healthy serum,TRSUT and TP-ELISA were detected in biological false positive.CONCLUSIONS The sensitivity and specificity of TRUST are the lowest.Thesensitivity and specificity of TP-ELISA are higher than TRUST,sensitivity and specificity of TPPA are the highest.TRSUT non-specific serological tests for syphilis can only be as a curative effect observation and follow-up whether relapse or reinfection indicators.
OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
OBJECTIVE To evaluate the three kinds of syphilis serologic test in the diagnosis of syphilis in the application.METHODS A total of 65 cases of syphilis positive sera and 96 healthy individuals negative sera were detected by TPHA,TP-ELISA,and the TPPA three methods.RESULTS TRUST was used to detecte 65 cases of syphilis in serum,61 cases of positive and negative in 4 cases,the positive rate of 93.8%.TP-ELISA detected out 65 cases of syphilis in serum,63 cases of positive and negative in 2 cases,positive rate of 96.9%.TPPT detected 65 cases of syphilis,65 cases of positive and negative 0 cases,the positive rate of 100%.Three methods tested 96 cases healthy serum,TRSUT and TP-ELISA were detected in biological false positive.CONCLUSIONS The sensitivity and specificity of TRUST are the lowest.Thesensitivity and specificity of TP-ELISA are higher than TRUST,sensitivity and specificity of TPPA are the highest.TRSUT non-specific serological tests for syphilis can only be as a curative effect observation and follow-up whether relapse or reinfection indicators.
Key concepts: Syphilis, Serology, Medicine, Internal medicine, Immunology, Gastroenterology, Antibody, Human immunodeficiency virus (HIV)