2012Chinese Journal of Thrombosis and HemostasisRequires access

Analysis to Improve the Accuracy of the Determination of D-dimer Immunoturbidimetric Assay

Xingfu Wu

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Abstract

Objective STAGO automatic coagulation analyzer,rational use of immune than three measurement mode of the turbidimetric method of quantitative determination of D-dimer,to provide accurate and reliable data for clinical.Methods STAGO-Evolution,France fully automated coagulation analyzer,quantitative determination of D/ C,D/ 3,D/ 4 of three measurement procedures,a total of 90 hybrid plasma specimens of D-dimer plasma levels,and normal/ abnormal D-dimer concentration level for repeatability and stability experiments.The data obtained using SPSS 13.0 software for statistical analysis.Results D-dimer level1.5 μg/ml three kinds of immune turbidimetric determination of D-dimer levels no significant differences in D dimer levels1.5 μg/ml the D/ C,and D/ 3 D/ 4 quantitative determination of D-dimer levels were significantly different.Conclusion In practical work,we should be for each hospital type of illness,according to the characteristics of their own laboratory,the rational use of instruments to measure program quantitative determination of D-dimer,to provide accurate and reliable for clinical D-dimer values,while saving the detection costs.

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Objective STAGO automatic coagulation analyzer,rational use of immune than three measurement mode of the turbidimetric method of quantitative determination of D-dimer,to provide accurate and reliable data for clinical.Methods STAGO-Evolution,France fully automated coagulation analyzer,quantitative determination of D/ C,D/ 3,D/ 4 of three measurement procedures,a total of 90 hybrid plasma specimens of D-dimer plasma levels,and normal/ abnormal D-dimer concentration level for repeatability and stability experiments.The data obtained using SPSS 13.0 software for statistical analysis.Results D-dimer level1.5 μg/ml three kinds of immune turbidimetric determination of D-dimer levels no significant differences in D dimer levels1.5 μg/ml the D/ C,and D/ 3 D/ 4 quantitative determination of D-dimer levels were significantly different.Conclusion In practical work,we should be for each hospital type of illness,according to the characteristics of their own laboratory,the rational use of instruments to measure program quantitative determination of D-dimer,to provide accurate and reliable for clinical D-dimer values,while saving the detection costs.

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Available abstract

Objective STAGO automatic coagulation analyzer,rational use of immune than three measurement mode of the turbidimetric method of quantitative determination of D-dimer,to provide accurate and reliable data for clinical.Methods STAGO-Evolution,France fully automated coagulation analyzer,quantitative determination of D/ C,D/ 3,D/ 4 of three measurement procedures,a total of 90 hybrid plasma specimens of D-dimer plasma levels,and normal/ abnormal D-dimer concentration level for repeatability and stability experiments.The data obtained using SPSS 13.0 software for statistical analysis.Results D-dimer level1.5 μg/ml three kinds of immune turbidimetric determination of D-dimer levels no significant differences in D dimer levels1.5 μg/ml the D/ C,and D/ 3 D/ 4 quantitative determination of D-dimer levels were significantly different.Conclusion In practical work,we should be for each hospital type of illness,according to the characteristics of their own laboratory,the rational use of instruments to measure program quantitative determination of D-dimer,to provide accurate and reliable for clinical D-dimer values,while saving the detection costs.

Key concepts: D-dimer, Repeatability, Medicine, Dimer, Spectrum analyzer, Coagulation, Chromatography, Gastroenterology

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