A Comparative Study of mifepristone and misoprostol on termination of 12-16 gestational weeks

Objective:To study the clinical effect and security of Mifepristone and Misoprostol applied on the termination of 12-16 gestational weeks.Methods:295 healthy pregnancy women with 12~16 gestational weeks were randomly divided into two groups including observation group(145 cases)with mifepristone and misoprostol and control group(150 cases)with transvaginal.Result:The success rates of abortion in observation group and control group were 96.6% and 80.7%,respectively(P0.05).There was a significant difference between the two groups in the time of Contractions time and induced abortion(P0.05).There were no significant differences between groups in uterine bleeding(P0.05).Conclusion:The application of mifepristone and misoprostol on terimination of 12-16 gestational weeks demonstrates advantages in high success rate,short time,simplicity,safety,it can be promotion.