Protection of reduced glutathione to postoperative liver function in patients with partial hepatectomy

Objective:To evaluate the protection of reduced glutathione and clinical therapeutic efficacy in patients with partial hepatectomy accompany with blocking fossa transversalis hepatic blood flow.Methods: A randomized controlled trial of parallel design,40 cases of patients with partially hepatectomized postoperative supplemented by reduced glutathione and a control group. Results: The index of the liver function during postoperative 1,3,7 d in treatment group including serum glutamate-pyruvate transaminase(ALT),aspartic acid transaminase(AST),and serum total bilirubin(TBIL),was better than the control group(P0.05).Albumen(ALB) on postoperative 1 d was higher than the control group(P0.05).The fatality and the incidence rate of complication among postoperative cases were no significant difference(P0.05).Postoperative average stay of the treatment group was shorter than the control group,but had no significant(P0.05). Conclusion: The reduced glutathione was a genuine therapeutic action in the development of postoperative liver function damage restoration,on the condition that patients with partially hepatectomized accompany with blocking fossa transversalis hepatic blood flow.It could have a certain degree of clinical use value.