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2008•Sichuan Mental HealthRequires access

A clinical comparative study of venlafaxiine and sertraline in the treatment of obsessive-compulsive disorders

Zhao Shu-hu

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Abstract

Objective To compare the efficacy and side efffects of venlafaxine and sertraline in the treatment of obsessive-compulsive disorders(OCD).Methods Seventy-two patients met CCMD-3 for OCD were randomly assigned to two groups.One groups was treated with venlafaxline and the other with sertraline for 8 weeks.The efficacy was measured was Yale-Brown Obsessive Compulsive Scale(Y-BOCS)and Hamilton Depression Scale(HAMD).The side effects were determined by the Treatment Emergent Symptom Scale(TESS).Results There were no significant between two groups in overall response showed by the reduction rates Y-BOCS and HAMD total scores.There was no significant difference in serious and the occur quotiety of the side-reactoin.Conclusion Venlafaxine was an effective drug in the treatment of OCD.

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What this paper is about

Objective To compare the efficacy and side efffects of venlafaxine and sertraline in the treatment of obsessive-compulsive disorders(OCD).Methods Seventy-two patients met CCMD-3 for OCD were randomly assigned to two groups.One groups was treated with venlafaxline and the other with sertraline for 8 weeks.The efficacy was measured was Yale-Brown Obsessive Compulsive Scale(Y-BOCS)and Hamilton Depression Scale(HAMD).The side effects were determined by the Treatment Emergent Symptom Scale(TESS).Results There were no significant between two groups in overall response showed by the reduction rates Y-BOCS and HAMD total scores.There was no significant difference in serious and the occur quotiety of the side-reactoin.Conclusion Venlafaxine was an effective drug in the treatment of OCD.

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Available abstract

Objective To compare the efficacy and side efffects of venlafaxine and sertraline in the treatment of obsessive-compulsive disorders(OCD).Methods Seventy-two patients met CCMD-3 for OCD were randomly assigned to two groups.One groups was treated with venlafaxline and the other with sertraline for 8 weeks.The efficacy was measured was Yale-Brown Obsessive Compulsive Scale(Y-BOCS)and Hamilton Depression Scale(HAMD).The side effects were determined by the Treatment Emergent Symptom Scale(TESS).Results There were no significant between two groups in overall response showed by the reduction rates Y-BOCS and HAMD total scores.There was no significant difference in serious and the occur quotiety of the side-reactoin.Conclusion Venlafaxine was an effective drug in the treatment of OCD.

Key concepts: Hamd, Sertraline, Venlafaxine, Depression (economics), Hamilton depression scale, Psychiatry, Psychology, Obsessive compulsive

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