2011•Zhongguo shiyan fangjixue zazhiRequires access

Optimization of Extraction Technology of Fructus Choerospondiatis by Orthogonal Test

Shengwang Liang

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Abstract

Objective:To optimize the extraction technology for traditional Mongolian medicine Fructus Choerospondiatis.Method:The extraction technology was optimized by orthogonal design with concentration of alcohol,amount of alcohol,extraction time and extraction times as factors.A RP-HPLC.Result:was established for determination of gallic acid;An UV-Spectrophotometer method was adopted to determine the content of total flavonoids.Result:The optimum extracting condition was as follows:adding eight times amount of 70% alcohol and refluxing and extracting for 1h(totally extracting for 2 times).Conclusion:The extraction technology was economic,feasible and controllable.

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Objective:To optimize the extraction technology for traditional Mongolian medicine Fructus Choerospondiatis.Method:The extraction technology was optimized by orthogonal design with concentration of alcohol,amount of alcohol,extraction time and extraction times as factors.A RP-HPLC.Result:was established for determination of gallic acid;An UV-Spectrophotometer method was adopted to determine the content of total flavonoids.Result:The optimum extracting condition was as follows:adding eight times amount of 70% alcohol and refluxing and extracting for 1h(totally extracting for 2 times).Conclusion:The extraction technology was economic,feasible and controllable.

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Available abstract

Objective:To optimize the extraction technology for traditional Mongolian medicine Fructus Choerospondiatis.Method:The extraction technology was optimized by orthogonal design with concentration of alcohol,amount of alcohol,extraction time and extraction times as factors.A RP-HPLC.Result:was established for determination of gallic acid;An UV-Spectrophotometer method was adopted to determine the content of total flavonoids.Result:The optimum extracting condition was as follows:adding eight times amount of 70% alcohol and refluxing and extracting for 1h(totally extracting for 2 times).Conclusion:The extraction technology was economic,feasible and controllable.

Key concepts: Extraction (chemistry), Gallic acid, Chromatography, Alcohol, High-performance liquid chromatography, Chemistry, Mathematics, Computer science

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