2013•China Medicine and PharmacyRequires access

Optimization of the extraction technology research of Fructus Arctii

Chen Miaodan

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Abstract

Objective To optimize the extraction process of Fructus Arctii. Methods The L 9 (3 4 )orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology,inspected the solvent concentration,solvent volume,extraction times on alcohol extraction process,each element of 3 levels,HPLC was used to analyze the content of Arctinin. Results The optimal alcohol extracting technology for fructus arctii:solvent concentration was 75%,the amount of solvent was 6 times of volume,the extraction times was one. Conclusion The optimum extraction process of Fructus Arctii is the Fructus Arctii powder, adding 6 times amount of volume 75% of ethanol extraction for 1 time,the extraction time is 2 h,the extraction rate of 95.49%,can be used as a laboratory method for extracting burdock.

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Objective To optimize the extraction process of Fructus Arctii. Methods The L 9 (3 4 )orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology,inspected the solvent concentration,solvent volume,extraction times on alcohol extraction process,each element of 3 levels,HPLC was used to analyze the content of Arctinin. Results The optimal alcohol extracting technology for fructus arctii:solvent concentration was 75%,the amount of solvent was 6 times of volume,the extraction times was one. Conclusion The optimum extraction process of Fructus Arctii is the Fructus Arctii powder, adding 6 times amount of volume 75% of ethanol extraction for 1 time,the extraction time is 2 h,the extraction rate of 95.49%,can be used as a laboratory method for extracting burdock.

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Available abstract

Objective To optimize the extraction process of Fructus Arctii. Methods The L 9 (3 4 )orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology,inspected the solvent concentration,solvent volume,extraction times on alcohol extraction process,each element of 3 levels,HPLC was used to analyze the content of Arctinin. Results The optimal alcohol extracting technology for fructus arctii:solvent concentration was 75%,the amount of solvent was 6 times of volume,the extraction times was one. Conclusion The optimum extraction process of Fructus Arctii is the Fructus Arctii powder, adding 6 times amount of volume 75% of ethanol extraction for 1 time,the extraction time is 2 h,the extraction rate of 95.49%,can be used as a laboratory method for extracting burdock.

Key concepts: Extraction (chemistry), Medicine, Chromatography, Solvent, Volume (thermodynamics), Alcohol, High-performance liquid chromatography, Traditional medicine

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