The clinical significance of β2-MG and LDH measuring in patients with MM

Objective To evaluate the clinical significance of the serum β2-microglobulin(β2-MG) and lactic dehydrogenase (LDH) measuring in MM patients. Methods The β2-MG and LDH are collected from 55 MM patients and measured by rate method and radioimmunoassay respectively. Results All samples are classified into phase I or phase Ⅱ or phase Ⅲ, group A or group B, chemotherapy complete remission or chemotherapy partial remission(CR or PR) accordingly for comparison prose. It are found that value of β2-MG and LDH for all patients in the later category of the comparison pair mentioned. Above are obviously higher than that in their comparison counterpart and the difference is of significance (P 0.05), while the difference for chemotherapy ineffective group before and after chemotherapy seems of less significance (P 0.05). Conclusion The level of β2-MG and LDH can be taken as an auxiliary clinical index to classify the phase of prognosis and effectiveness of treatment in MM patients.