Comparison of the Two Modeling Methonds for Qi Stagnation and Blood Stasis

Objective:To compare methods of rat modeling for Qi stagnation and blood stasis for serving the experimental of etiological factors and pathogenesis.Methods:Apply various stimulations such as noise,light,electricity,tail-clamping, icewater-bath,bondage and adrenaline injection to establish the rat mode.Adopt the pressure sensing technology of MOTO to detect hemorheology-related indicators,use the coagulation method to detect coagulation-related indicators. Results:In hemorheology,compared with the negative control group,the viscosity of whole blood of high,medium,low shear and plasma viscosity increased in the multi -factor stimulation group(P0.05).The viscosity of whole blood of high shear and plasma viscosity increased in the adrenaline injection group(P0.05).The fibrinogen content in blood coagulation indicated significant increase in both group(P0.05 ).Conclusion:Both multi-factor stimulation and adrenaline injection can lead to blood stasis.Adrenaline injection method can be convenient and easy.Multi-factor stimulation group relatively conform the theory of etiology and pathogenesis.