2011Laboratory Medicine and ClinicRequires access

Comparative analysis on seven detection systems for testing of fresh plasma glucose

Luo Xiu-lin

Open publisher page 0 citations

Abstract

Objective To evaluate comparability of different detection systems for determination of blood glucose through bias estimation and method comparison,and ensure the clinical quality requirements.Methods Compared with OLYMPUS AU2700 dection system,50 cases of fresh blood plasma samples were detected glucose with different detcetion systems,including electrochemical method,dry chemical method and spectrophotometric method.Results The variation coefficient of different detection systems was less than 5.0%;The correlation coefficient between the various systems was more than 0.975;The overall difference between systems was not statistically significant(P0.01);Compared with a traceable target detection system 1,Detection system 3,detection system 4,and detection system 7 exceeded the range of T ± 5%,Detection system 2,detection system 5,and detection system 6 were in the range of T ± 5% in the three medical decision levels.Conclusion There are bias in part of the different detection systems for glucose detection results,but the results are comparable through corrective measures.

About this research paper

What this paper is about

Objective To evaluate comparability of different detection systems for determination of blood glucose through bias estimation and method comparison,and ensure the clinical quality requirements.Methods Compared with OLYMPUS AU2700 dection system,50 cases of fresh blood plasma samples were detected glucose with different detcetion systems,including electrochemical method,dry chemical method and spectrophotometric method.Results The variation coefficient of different detection systems was less than 5.0%;The correlation coefficient between the various systems was more than 0.975;The overall difference between systems was not statistically significant(P0.01);Compared with a traceable target detection system 1,Detection system 3,detection system 4,and detection system 7 exceeded the range of T ± 5%,Detection system 2,detection system 5,and detection system 6 were in the range of T ± 5% in the three medical decision levels.Conclusion There are bias in part of the different detection systems for glucose detection results,but the results are comparable through corrective measures.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To evaluate comparability of different detection systems for determination of blood glucose through bias estimation and method comparison,and ensure the clinical quality requirements.Methods Compared with OLYMPUS AU2700 dection system,50 cases of fresh blood plasma samples were detected glucose with different detcetion systems,including electrochemical method,dry chemical method and spectrophotometric method.Results The variation coefficient of different detection systems was less than 5.0%;The correlation coefficient between the various systems was more than 0.975;The overall difference between systems was not statistically significant(P0.01);Compared with a traceable target detection system 1,Detection system 3,detection system 4,and detection system 7 exceeded the range of T ± 5%,Detection system 2,detection system 5,and detection system 6 were in the range of T ± 5% in the three medical decision levels.Conclusion There are bias in part of the different detection systems for glucose detection results,but the results are comparable through corrective measures.

Key concepts: Detection limit, Coefficient of variation, Correlation coefficient, Chromatography, Comparability, Computer science, Chemistry, Statistics

Related papers

Back to paper searchBrowse research topicsOriginal source
Comparative analysis on seven detection systems for testing of fresh plasma glucose — Research Paper | ScholarLens