2010•Unpublished venueRequires access
Research on the comparability of total prostate specific antigen result measured with different kinds of assay system
Huiling Liu
Open publisher page 0 citations
Abstract
Objective To study the comparability of total prostate specific antigen(TPSA)results obtained with different detection system.Methods 4 kinds of chemiluminescence immunoassay system(ABBOTT AXSYM,Roche2010,Beckmancoulter Access and DPC immulite-1000)were used to detect TPSA concentration in 2 kinds of quality control specimenC Bayer and DPOand 38 patient samples of different concentration.The results were analyzed with statistics methods.Results Analysis of variance showed that TPSA results from different controls an d patient samples had significant difference in different assay system(P0.01).The correlation coefficient of each detection system was above 0.980 and the reliability coefficient of them was closed to 1.When Johnson VITROS ECI Was regarded as a target detection system in order to evaluate the acceptability of other detection system,all detection ystems in our study could be accepted by clinic assessment.Conclusion The precision of TPSA results in the 4 kinds of detection system accord to clinical requirement.Comparability exists in the evaluation of clinical acceptability.