Effects of aripiprazole and clozapine on life quality of schizophrenics

Objective: To compare the effects of aripiprazole and clozapine on the life quality of schizophrenics. Method:Sixty schizophrenic patients were randomly divided into aripiprazole group (n=30) and clozapine group (n=30) for eight weeks.Positive and negative syndrome scale (PANSS) and quality of life scale (QOL) were administered before treatment and at the end of 8 week treatment. Results:Both aripiprazole and clozapine group showed psychotic symptoms and life quality improvement in terms of PANSS and QOL,but aripiprazole group improve more than clozapine group in physiological and psychological domain,interpersonal relationship,independence and environment. Conclusion: Aripiprazole can improve life quality of schizophrenic patients and benefit them for returning to society.