Drug resistance of 104 strains of staphylococcus aureus

OBJECTIVE To explore the drug resistance of Staphylococcus aureus to commonly used antimicrobial agents and offer data for reasonable antimicrobial agents in clinic.METHODS One hundred four strains of Staphylococcus aureus were analyzed antimicrobial susceptibility test with the disk diffusion procedure.RESULTS Of 104 strains of S.aureus,68.3% of which were from sputum,the next was secretion,accounting for 18.3%.meticillin resistant staphylococcus aureus(MRSA) was 73,accounting for 70.2%,meticillin sensitive staphylococcus aureus(MSSA) was 31,accounting for 29.8%.The sensitive rates of MRSA and MSSA to vancomycin were all 100%.MRSA had multi-resistance to antibiotics that commonly used clinically,to Penicillin,Oxacillin and Ampicillin,the rate of antibiotic resistance of MRSA was 100% respectively,the resistance to Ciprofloxacin,Erythromycin,Gentamicin,tetracycline,SMZ-TMP and Rifampicin of MRSA was 83.6%,84.9%,86.3%,97.3%,20.6% and 47.9%.The resistance to Penicillin,Ampicillin,Erythromycin,Gentamicin and Clindamycin of MSSA was 96.8%,87.2%,74.2%,35.5% and 38.7%.CONCLUSION S.aureus isolated from clinic has multiple resistance to commonly used antimicrobial resistance,especially MRSA strains,different treatment protocols should be chosen according to the drug-resistant characteristics of isolated strains.