Antimicrobial resistance of 253 Staphylococcus aureus strains

Objective To investigate the distribution and antimicrobial resistance of Staphylococcus aureus for the guidance of rational use of antibiotics.Methods The S.aureus from May 2010 to April 2011were analyzed retrospectively.Vitek-AMS automated system was applied to the identification and drug sensitivity test.Results A total of 253 S.aureus strains were isolated from sputum(51.4%).The departments with the highest distribution were the neurology(29.5%),ICU(15.8%),and neurolsurgery(7.5%).Among them,165(52.2%) strains were found to be MRSA,and 70.0% of these MRSA strains were found resistant to multiple antibiotics.88(47.8%) strains were MSSA which were sensitive to most of antibiotics,except penicillin and erythromycin.No strains were found resistant to vancomycin.Conclusion The isolation rate of MRSA increased significantly;the drug resistance status is very serious,indicating that it is necessary to routinely monitor MRSA occurrence and use antibiotics according to the sensitiveity tests results.