Clinical Observe of Omeprazole and Famotidine in Treating 68 Peptic ulcer

Objective To observe the clinical effects and adverse reactions of omeprazole and famotidine on peptic ulcer. Methods 68 patients with pepti c ulcer were randomly divided into 2 gyoups.Treated with omeprazole or famotidine respectively. The treated group received omeprazole 20mg,P.O,qd.The con- trast group received famotidine 20mg,P.O,Bid.Period of treatment for two groups were 4-week. Results 4-week effective rate of omeprazole group 96.0% and famotidine group 88.0% respectively. Indicating significant differences between the 2 groups (P0.05). A few of adverse reactions appeared in the omeprazole group 17.0% and less in the famotidine group12.0% (P0.05).but the adverse reactions disappeared spontaneously. Conclusion Omeprazole is still safer and more effective drug in treating pepti culcer.