2008Medical Journal of Chinese People's HealthRequires access

Contrast Study of Treating Schizophrenia by Risperidone Capsule and Risperidone Tablet

Y Chen

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Abstract

Objective:To explore Risperidone Capsule treatment on schizophrenia and the side effects.Methods:Total 72 cases of patients with schizophrenia were randomly divided into Risperidone Capsule group(36 cases),Risperidone Tablet(36 cases),Carrying on the clinical check experiment,two groups of medicin average therapeutic dose respectively is 5±1.82 mg/d,4.2±1.29 mg/d,the treatment course is 8 weeks.Indicators include the effect of positive and negative symptom scale(PANSS),adverse reactions indicators for adverse reactions Symptom Rating Scale(TESS) and the laboratory.Results: At the end of treatment,two groups PANSS score in the group,were significantly reduced(P0.01).By PANSS total points: Risperidone Capsule group(50.38±(11.3))%,Risperidone Tablet group(51.85±12.4)%;The total efficiency: Risperidone Capsule 86.11%,Risperidone Tablet 88.88%.There is no significant difference in the two groups(P0.05).Conclusions: Risperidone Capsule is an effective,safe drug type,as new atypical antipsychotic to treat schizophrenia.But there is significant difference in average therapeutic dose and time go into effect to compared with Risperidone Tablet(P0.05).

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Objective:To explore Risperidone Capsule treatment on schizophrenia and the side effects.Methods:Total 72 cases of patients with schizophrenia were randomly divided into Risperidone Capsule group(36 cases),Risperidone Tablet(36 cases),Carrying on the clinical check experiment,two groups of medicin average therapeutic dose respectively is 5±1.82 mg/d,4.2±1.29 mg/d,the treatment course is 8 weeks.Indicators include the effect of positive and negative symptom scale(PANSS),adverse reactions indicators for adverse reactions Symptom Rating Scale(TESS) and the laboratory.Results: At the end of treatment,two groups PANSS score in the group,were significantly reduced(P0.01).By PANSS total points: Risperidone Capsule group(50.38±(11.3))%,Risperidone Tablet group(51.85±12.4)%;The total efficiency: Risperidone Capsule 86.11%,Risperidone Tablet 88.88%.There is no significant difference in the two groups(P0.05).Conclusions: Risperidone Capsule is an effective,safe drug type,as new atypical antipsychotic to treat schizophrenia.But there is significant difference in average therapeutic dose and time go into effect to compared with Risperidone Tablet(P0.05).

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Available abstract

Objective:To explore Risperidone Capsule treatment on schizophrenia and the side effects.Methods:Total 72 cases of patients with schizophrenia were randomly divided into Risperidone Capsule group(36 cases),Risperidone Tablet(36 cases),Carrying on the clinical check experiment,two groups of medicin average therapeutic dose respectively is 5±1.82 mg/d,4.2±1.29 mg/d,the treatment course is 8 weeks.Indicators include the effect of positive and negative symptom scale(PANSS),adverse reactions indicators for adverse reactions Symptom Rating Scale(TESS) and the laboratory.Results: At the end of treatment,two groups PANSS score in the group,were significantly reduced(P0.01).By PANSS total points: Risperidone Capsule group(50.38±(11.3))%,Risperidone Tablet group(51.85±12.4)%;The total efficiency: Risperidone Capsule 86.11%,Risperidone Tablet 88.88%.There is no significant difference in the two groups(P0.05).Conclusions: Risperidone Capsule is an effective,safe drug type,as new atypical antipsychotic to treat schizophrenia.But there is significant difference in average therapeutic dose and time go into effect to compared with Risperidone Tablet(P0.05).

Key concepts: Risperidone, Schizophrenia (object-oriented programming), Capsule, Negative symptom, Adverse effect, Medicine, Side effect (computer science), Internal medicine

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