Comparison of Morphine and Sufentanil in Postoperative Patient-controlled Epidural Analgesia for Patients undergone Hysterectomy

Objective To compare the clinical effects and side-effects of morphine and sufentanil in postoperative patient-controlled epidural analgesia (PCEA). Methods Eighty patients (ASAⅠ~Ⅱ) undergone hysterectomy were randomly divided into two groups: morphine group (group M, n=40) and sufentanil group (group SF, n=40). Group M were given morphine for postoperative PCEA and group SF with sufentanil. Visual analogue scales(VAS), Ramsay scales and side-effects including pruritus, nausea and emesis were assessed after 4, 8, 12, 24 and 48h of postoperative analgesia. Results The VAS scores and Ramsay scales scores were of no signifi cant difference between two groups (P0.05). The incidence of side-effects including pruritus, nausea and emesis was signifi cantly higher in group M than that in group SF (P0.05). Conclusion Small dose of sufentanil in postoperative PCEA can obtain a satisfactory analgesia effect and fewer side-effects.