2014China Medicine and PharmacyRequires access

Study of efficacy and economics of antiviral treatment of decompensated liver cirrhosis following hepatitis B

Wang Fuqu

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Abstract

Objective To observe the differences in clinical efficacy and economic benefits between the two groups of patients with decompensated liver cirrhosis following hepatitis B who received antiviral treatment and ordinary liver protection treatment respectively. Methods 155 patients with decompensated liver cirrhosis following hepatitis B who were admitted to our hospital were selected, of which 98 patients received antiviral treatment(experimental group) and 57 patients only received ordinary liver protection treatment(control group). After treatment, clinical efficacy of the two groups was observed and meanwhile their economic costs and effects were analyzed. Results Five patients died in the experimental group and 18 patients died in the control group, accounting for 78.2% of the total death rate. The experimental group had significantly better clinical efficacy than the control group(P 0.05); In terms of economic cost and effect analysis, the experimental group had significantly lower economic cost than the control group(P0.05). Conclusion In the treatment of decompensated liver cirrhosis following hepatitis B, antiviral drug treatment has good efficacy and low cost, which is an important treatment method for the patients with decompensated liver cirrhosis following hepatitis B.

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Objective To observe the differences in clinical efficacy and economic benefits between the two groups of patients with decompensated liver cirrhosis following hepatitis B who received antiviral treatment and ordinary liver protection treatment respectively. Methods 155 patients with decompensated liver cirrhosis following hepatitis B who were admitted to our hospital were selected, of which 98 patients received antiviral treatment(experimental group) and 57 patients only received ordinary liver protection treatment(control group). After treatment, clinical efficacy of the two groups was observed and meanwhile their economic costs and effects were analyzed. Results Five patients died in the experimental group and 18 patients died in the control group, accounting for 78.2% of the total death rate. The experimental group had significantly better clinical efficacy than the control group(P 0.05); In terms of economic cost and effect analysis, the experimental group had significantly lower economic cost than the control group(P0.05). Conclusion In the treatment of decompensated liver cirrhosis following hepatitis B, antiviral drug treatment has good efficacy and low cost, which is an important treatment method for the patients with decompensated liver cirrhosis following hepatitis B.

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Available abstract

Objective To observe the differences in clinical efficacy and economic benefits between the two groups of patients with decompensated liver cirrhosis following hepatitis B who received antiviral treatment and ordinary liver protection treatment respectively. Methods 155 patients with decompensated liver cirrhosis following hepatitis B who were admitted to our hospital were selected, of which 98 patients received antiviral treatment(experimental group) and 57 patients only received ordinary liver protection treatment(control group). After treatment, clinical efficacy of the two groups was observed and meanwhile their economic costs and effects were analyzed. Results Five patients died in the experimental group and 18 patients died in the control group, accounting for 78.2% of the total death rate. The experimental group had significantly better clinical efficacy than the control group(P 0.05); In terms of economic cost and effect analysis, the experimental group had significantly lower economic cost than the control group(P0.05). Conclusion In the treatment of decompensated liver cirrhosis following hepatitis B, antiviral drug treatment has good efficacy and low cost, which is an important treatment method for the patients with decompensated liver cirrhosis following hepatitis B.

Key concepts: Medicine, Cirrhosis, Internal medicine, Gastroenterology, Antiviral treatment, Hepatitis B, Clinical efficacy, Hepatitis

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