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2007•Journal of RadioimmunologyRequires access

Application of Determination of Serum CA72-4,CA19-9 Levels for Diagnosis in Patients with Gastric Carcinoma

Pla Oncology

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Abstract

Objective To explore the applicability of determination of serum CA72-4、CA19-9 levels for diagnosis of gastric carcinoma.Methods Serum levels of CA72-4 and CA19-9 were determined with RIA in 175 patients with gastric carcinoma.Results With CA72-4 and CA19-9,the diagnostic sensitivity for gastric carcinoma was 45.1% and 47.4% respectively.With combined determinations of CA72-4 and CA19-9,the sensitivity was enhanced to 60.6%.The sentivity of serum CA72-4 and CA19-9 in patients with stage Ⅲ～Ⅳ gastric carcinoma was significantly higher than that in the patients with stage Ⅰ～Ⅱ gastric cancer.Conclusion Serum CA72-4 and CA19-9 determination was helpful for diagnosis of gastric carcinoma combined determination of two markers was more sensitive.

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What this paper is about

Objective To explore the applicability of determination of serum CA72-4、CA19-9 levels for diagnosis of gastric carcinoma.Methods Serum levels of CA72-4 and CA19-9 were determined with RIA in 175 patients with gastric carcinoma.Results With CA72-4 and CA19-9,the diagnostic sensitivity for gastric carcinoma was 45.1% and 47.4% respectively.With combined determinations of CA72-4 and CA19-9,the sensitivity was enhanced to 60.6%.The sentivity of serum CA72-4 and CA19-9 in patients with stage Ⅲ～Ⅳ gastric carcinoma was significantly higher than that in the patients with stage Ⅰ～Ⅱ gastric cancer.Conclusion Serum CA72-4 and CA19-9 determination was helpful for diagnosis of gastric carcinoma combined determination of two markers was more sensitive.

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Available abstract

Objective To explore the applicability of determination of serum CA72-4、CA19-9 levels for diagnosis of gastric carcinoma.Methods Serum levels of CA72-4 and CA19-9 were determined with RIA in 175 patients with gastric carcinoma.Results With CA72-4 and CA19-9,the diagnostic sensitivity for gastric carcinoma was 45.1% and 47.4% respectively.With combined determinations of CA72-4 and CA19-9,the sensitivity was enhanced to 60.6%.The sentivity of serum CA72-4 and CA19-9 in patients with stage Ⅲ～Ⅳ gastric carcinoma was significantly higher than that in the patients with stage Ⅰ～Ⅱ gastric cancer.Conclusion Serum CA72-4 and CA19-9 determination was helpful for diagnosis of gastric carcinoma combined determination of two markers was more sensitive.

Key concepts: CA19-9, Medicine, Gastric carcinoma, Internal medicine, Gastroenterology, Cancer, Carcinoma, Stage (stratigraphy)

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Application of Determination of Serum CA72-4,CA19-9 Levels for Diagnosis in Patients with Gastric Carcinoma — Research Paper | ScholarLens