Application of total intravenous anesthesia with remifentanil and sufentanil in gynecological laparoscopic operation

Objective To compare the characteristics of remifentanil and sufentanil for tracheal intubation general anesthesia in gynecological laparoscopic operation. Methods 80 patients received gynecological laparoscopic operation were randomly divided into the remifentanil group and the sufentanil group with 40 patients in each group,and they were performed total intravenous anesthesia with remifentanil or sufentanil respectively. Compare the changes of heart rate,mean arterial pressure in the two groups before and after induction,at the time of intubation,pneumoperitoneum,and after the operation. And differences in two groups were recorded in the recovery time,extubation time,postoperative pain in 24 hours,exhaust time and postoperative complications. Results Change trend and magnitude in heart rate,mean arterial pressure had no significant difference in the two groups( P 0. 05). The recovery time,extubation time in remifentanil group was shorter( P 0. 01),postoperative pain in 24 hours in sufentanil group was more mild( P 0. 01). Exhaust time and postoperative complications of the two groups had no significant difference( P 0. 05). Conclusion Remifentanil and sufentanil used in gynecological laparoscopic operation can achieve good effect. and effects of the two drugs on hemodynamics were similar. Remifentanil can recieve better effect in terms of recovery time,while sufentanil has better postoperative analgesia effect.