The Application of Sufentanil Combined with Remifentanil for Patients in Laparoscopic Cholecystectomy

Objective To investigate the advantages of sufentanil combined with fentnyl in laparoscopic cholecystectomy. Methods Sixty ASA grade I-II patients, scheduled for laparoscopic cholecystectomy under general anesthesia were randomly divided into remifentanil group(R, n=30)and sufentanil-remifentanil grorp (SR, n=30). Group R were given remifentanil 1μg/kg in anesthesia induction and maintained with 0.1μg/kg/min; Group SR were given sufentanil 0.5μg/kg in anesthesia induction and maintained with remifentanil 0.1μg/kg/min. The changes of SBP and HR were observed during anesthesia. The recovery of spontaneous breathing time, waking time, extubation time and complication related to recocery and extubation were recorded. VAS and agitation emergence score were measured during postoperation. Result Both two groups had good hemodynamic stability during anesthesia induction and operative procedure. Group SR had lower VAS score and lower agitation score compared to group R postoperatively (P0.05). Conclusion Sufentanil for anesthesia induction and Remifentanil for anesthesia maintaining had good hemodynamic stability during introperative procedure and had better postoperative recovery quality for patients undergoing laparoscopic cholecystectomy.