Effects of dezocine combined with fentanyl on patient-controlled intravenous analgesia after thoracic surgery

Objective To evaluate the effect of dezocine combined with fentanyl on patient-controlled intravenous analgesia(PCIA) after thoracic surgery.Methods Eighty patients admitted in Yuebei People's Hospital hospital with American Society of Anesthesiologists(ASA)Ⅰ-Ⅱ were scheduled for thoracic surgery and randomly divided into fentanyl group(group F)and dezocine combined with fentanyl group(group DF).There were 40 patients in each group.Intravenous anesthesia with tracheal intubation and PCIA were performed in all the patients.In group DF,dezocine 0.4 mg/kg and fentany 10 μg/kg with 0.9% normal saline diluted to 100 ml;and in group F,fentanyl 20 μg/kg with 0.9%normal saline diluted to 100 ml.Visual analogue scale(VAS),Ramsay scores and adverse reactions were recorded at 4,8,12,24 and 48 h after operation.Results There was no significant difference in VAS score or Ramsay score(P0.05).Compared with group F,group DF had less consumption of fentanyl at each time point(P0.01).The total incidence rates of adverse reactions in group F and group DF were 47.3%and 8.7%.(P0.05).Conclusion PCIA with dezocine combined with fentanyl is an effective method for the postoperative analgesia in thoracic surgery.It can reduce the consumption of fentanyl and have high patient satisfaction and low incidence of adverse reactions.