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2010•Science and Technology of Food IndustryRequires access

Study on α-glucosidase inhibitory activity of extracts from Musa basjoo Sieb. et Zucc.

Wenyi Kang

Open publisher page 3 citations

Abstract

The α-glucosidase inhibitory activities of different extracts from root and flower of Musa basjoo Sieb. et Zucc. were screened in vitro and the results were compared with Acarbose as positive control. The results showed that root and flower of M. basjoo had activity. In six extracts of M. basjoo,except for the ethyl acetate extract and the n-butanol extract of flower,they all had higher inhibitory activity than that of Acarbose(IC50=1103.01μg · mL-1). And the petroleum ether extract of root and flower had the highest inhibitory activity of α-glucosidase(IC50=32.03μg·mL-1,49.37μg·mL-1). In different parts of M. basjoo,the inhibitory activity of root was higher than that of flower. Different polar solvent extracts of same part also showed that petroleum ether extract had higher inhibitory activity than that of ethyl acetate extract and n-butanol extract.

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The α-glucosidase inhibitory activities of different extracts from root and flower of Musa basjoo Sieb. et Zucc. were screened in vitro and the results were compared with Acarbose as positive control. The results showed that root and flower of M. basjoo had activity. In six extracts of M. basjoo,except for the ethyl acetate extract and the n-butanol extract of flower,they all had higher inhibitory activity than that of Acarbose(IC50=1103.01μg · mL-1). And the petroleum ether extract of root and flower had the highest inhibitory activity of α-glucosidase(IC50=32.03μg·mL-1,49.37μg·mL-1). In different parts of M. basjoo,the inhibitory activity of root was higher than that of flower. Different polar solvent extracts of same part also showed that petroleum ether extract had higher inhibitory activity than that of ethyl acetate extract and n-butanol extract.

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Available abstract

The α-glucosidase inhibitory activities of different extracts from root and flower of Musa basjoo Sieb. et Zucc. were screened in vitro and the results were compared with Acarbose as positive control. The results showed that root and flower of M. basjoo had activity. In six extracts of M. basjoo,except for the ethyl acetate extract and the n-butanol extract of flower,they all had higher inhibitory activity than that of Acarbose(IC50=1103.01μg · mL-1). And the petroleum ether extract of root and flower had the highest inhibitory activity of α-glucosidase(IC50=32.03μg·mL-1,49.37μg·mL-1). In different parts of M. basjoo,the inhibitory activity of root was higher than that of flower. Different polar solvent extracts of same part also showed that petroleum ether extract had higher inhibitory activity than that of ethyl acetate extract and n-butanol extract.

Key concepts: Acarbose, Petroleum ether, Ethyl acetate, Chemistry, IC50, Traditional medicine, Ethanol, Inhibitory postsynaptic potential

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