Analysis of 61 cases with primary biliary cirrhosis

Objective:To summarize the clinical manifestations,laboratory examination in primary biliary cirrhosis(PBC),to raise awareness of the disease.Methods:Retrospective analysis was carried out on 61 cases with PBC and 50 patients with non-primary biliary cirrhosis(8 cases of autoimmune hepatitis,22 cases of hepatitis B,10 cases of hepatitis C,10 cas es of alcoholic hepatitis).Results:①Among the 61 patients,55 cases were female(90.1%),6 cases were male(9.9%),with a significant difference(P0.01);②Among 61 patients,35 cases(57.4%)were asymptomatic and 26 cases(42.6%) were symptoms,mainly for skin itching,fatigue and jaundice;③All of patients AMA were 100% positive and had a significant difference(P0.01),comparing with non-primary biliary cirrhosis;④ ALP,TBA and r-GT were significantly higher,while ALT and AST were moderately higher,TBil slightly higher.Conclusion:PBC is an autoimmune disease.Clinical workers should strengthen the awareness of PBC and attach importance to the AMA detection,particularly for the long-term unexplained female patients with abnormal liver function.