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2010•Linchuang gandanbing zazhiRequires access

Clinical analysis of 19 male patients with primary biliary cirrhosis

Shi Guangying

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Abstract

Objective To evaluate the clinical features,laboratory tests in male patients with primary biliary cirrhosis(PBC). Methods The clinical data of 19 cases were analyzed retrospectively. Results 17 cases(89%)were middle-elderly aged with mean age of 54±17yr;7 case(s36.7%)were asymptomatic,and 9 case(s47.7%)were decompen- sated hepatic cirrhosis;The AMA in 13 patient(s68.4%)and AMA-M2 in 14(73.7%)were positive;With ursodeoxycholic acid treatment,patients in early stage improved. Conclusion Male patients with PBC have relatively mild clinical symptoms and low autoantibodies,which make the early diagnosis even hard.

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What this paper is about

Objective To evaluate the clinical features,laboratory tests in male patients with primary biliary cirrhosis(PBC). Methods The clinical data of 19 cases were analyzed retrospectively. Results 17 cases(89%)were middle-elderly aged with mean age of 54±17yr;7 case(s36.7%)were asymptomatic,and 9 case(s47.7%)were decompen- sated hepatic cirrhosis;The AMA in 13 patient(s68.4%)and AMA-M2 in 14(73.7%)were positive;With ursodeoxycholic acid treatment,patients in early stage improved. Conclusion Male patients with PBC have relatively mild clinical symptoms and low autoantibodies,which make the early diagnosis even hard.

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Available abstract

Objective To evaluate the clinical features,laboratory tests in male patients with primary biliary cirrhosis(PBC). Methods The clinical data of 19 cases were analyzed retrospectively. Results 17 cases(89%)were middle-elderly aged with mean age of 54±17yr;7 case(s36.7%)were asymptomatic,and 9 case(s47.7%)were decompen- sated hepatic cirrhosis;The AMA in 13 patient(s68.4%)and AMA-M2 in 14(73.7%)were positive;With ursodeoxycholic acid treatment,patients in early stage improved. Conclusion Male patients with PBC have relatively mild clinical symptoms and low autoantibodies,which make the early diagnosis even hard.

Key concepts: Medicine, Ursodeoxycholic acid, Primary biliary cirrhosis, Asymptomatic, Internal medicine, Gastroenterology, Cirrhosis, Stage (stratigraphy)

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