2013•Anhui nongye kexueRequires access

Study of Antioxidant Effects of L-carnitine on Rabbit

XU Yon

Abstract

[Objective]To study antioxidant effects of LC,and investigate the effect of LC on SOD,GSH-PX,CAT,T-AOC and MDA in the blood,brain tissue and CSF of rabbit.[Method]A single dose of 1 ml / kg LC was taken orally to New Zealand rabbits with big ears.The plasma,brain tissue and CSF samples were taken and measured before and after administration respectively.[Result] After LC administration,SOD,GSH-PX CAT,and T-AOC activity in blood,brain tissue and cerebrospinal fluid significantly increased(P 0.05),while MDA significantly decreased(P 0.05).[Conclusion]LC shows antioxidant effects in rabbit.

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Key concepts: Antioxidant, Brain tissue, Cerebrospinal fluid, Carnitine, Chemistry, Rabbit (cipher), Glutathione, Pharmacology