Preliminary Analysis of Mycoplasma and Chlamydia Infection in Infertility in Xiangyang
Lihua Sun
Abstract
Lihua Sun
Abstract
Objective explore the relationship of ureaplasma urealyticum(UU), Mycoplasma hominis(MH) and Chlamydia trachomatis(CT) infection and anti sperm antibody(As Ab) with infertility. Methods with the clinical specimens of 1031 patients with infertility were used in Xiangyang City, culture and amplification of Mycoplasma and Chlamydia detection urogenital secretions in PCR method, the detection of serum As Ab with ELISA method,and normally control. Result Mycoplasma and Chlamydia infection rate of the patients with infertility and the As Ab positive rate was higher than that in normal control group, and the difference has statistical significance;the total positive rate of mycoplasma detection in serum of patients with As Ab is higher than that of negative patients; UU infection is the most common in mycoplasma infection. Conclusion Mycoplasma and Chlamydia infection and the production of As Ab are closely related to infertility. Infertility patients should test Mycoplasma and Chlamydia and As Ab regularly to avoid the risk of infertility; Mycoplasma positive should take medicine scientifically based on the drug sensitivity to enhance the treatment effect and prevent the emergence of drug resistance.
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Objective explore the relationship of ureaplasma urealyticum(UU), Mycoplasma hominis(MH) and Chlamydia trachomatis(CT) infection and anti sperm antibody(As Ab) with infertility. Methods with the clinical specimens of 1031 patients with infertility were used in Xiangyang City, culture and amplification of Mycoplasma and Chlamydia detection urogenital secretions in PCR method, the detection of serum As Ab with ELISA method,and normally control. Result Mycoplasma and Chlamydia infection rate of the patients with infertility and the As Ab positive rate was higher than that in normal control group, and the difference has statistical significance;the total positive rate of mycoplasma detection in serum of patients with As Ab is higher than that of negative patients; UU infection is the most common in mycoplasma infection. Conclusion Mycoplasma and Chlamydia infection and the production of As Ab are closely related to infertility. Infertility patients should test Mycoplasma and Chlamydia and As Ab regularly to avoid the risk of infertility; Mycoplasma positive should take medicine scientifically based on the drug sensitivity to enhance the treatment effect and prevent the emergence of drug resistance.
Key concepts: Mycoplasma, Infertility, Chlamydia, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, Male infertility