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2005•Journal of Guangdong Medical CollegeRequires access

Genital tract infection of Ureaplasma urealyticum and Mycoplasma hominis and serum anti-endometrial antibody in infertile women

Yihua Cai

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Abstract

Objective: To study the relationship between Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) infection and anti-endometrial antibody (AEMAb)in infertile women. Methods: UU and MH in cervical secretions and serum AEMAb level in 139 women with primary infertility, 167 with secondary infertility and 102 controls were determined by culture and ELISA, respectively. Results: Positive rates of UU, MH and AEMAb in infertile group were significantly higher than that in control group (P0.01), but there were no statistical differences between primary and secondary infertility (P0.05). The detection rate of AEMAb in infertile patients with mycoplasma were superior to that without mycoplasma (P0.01). Conclusion: Genital tract infection of UU and MH and immunological factor could be related to female infertility. AEMAb formation may be induced by mycoplasma infection.

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Objective: To study the relationship between Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) infection and anti-endometrial antibody (AEMAb)in infertile women. Methods: UU and MH in cervical secretions and serum AEMAb level in 139 women with primary infertility, 167 with secondary infertility and 102 controls were determined by culture and ELISA, respectively. Results: Positive rates of UU, MH and AEMAb in infertile group were significantly higher than that in control group (P0.01), but there were no statistical differences between primary and secondary infertility (P0.05). The detection rate of AEMAb in infertile patients with mycoplasma were superior to that without mycoplasma (P0.01). Conclusion: Genital tract infection of UU and MH and immunological factor could be related to female infertility. AEMAb formation may be induced by mycoplasma infection.

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Available abstract

Objective: To study the relationship between Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) infection and anti-endometrial antibody (AEMAb)in infertile women. Methods: UU and MH in cervical secretions and serum AEMAb level in 139 women with primary infertility, 167 with secondary infertility and 102 controls were determined by culture and ELISA, respectively. Results: Positive rates of UU, MH and AEMAb in infertile group were significantly higher than that in control group (P0.01), but there were no statistical differences between primary and secondary infertility (P0.05). The detection rate of AEMAb in infertile patients with mycoplasma were superior to that without mycoplasma (P0.01). Conclusion: Genital tract infection of UU and MH and immunological factor could be related to female infertility. AEMAb formation may be induced by mycoplasma infection.

Key concepts: Ureaplasma urealyticum, Mycoplasma hominis, Infertility, Mycoplasma, Primary infertility, Genital tract, Antibody, Medicine

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