2008•Lishizhen Medicine and Materia Medica ResearchRequires access

Determination of Synthetic Borneol in Naotong Injection by Gas Chromatography

Cao Hong

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Abstract

Objective To establish the determination for synthetic borneol in Naotong Injection by GC.Methods The internal standard method was employed.Naphthalene,the internal standard,was added to the sample before treatment.The GC system consisted of DB-WAX column(30 m×0.32 mm,0.25 μm),nitrogen as the carrier gas,column temperature at 130℃,and FID as the detector.Results Synthetic borneol(borneol and isoborneol) and naphetalene were separated well under the chromatographic condition.The average recovery of synthetic borneol was 96.58%.Conclusion The method is sensitive,accurate,and can be used to control the quality of the preparation.

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What this paper is about

Objective To establish the determination for synthetic borneol in Naotong Injection by GC.Methods The internal standard method was employed.Naphthalene,the internal standard,was added to the sample before treatment.The GC system consisted of DB-WAX column(30 m×0.32 mm,0.25 μm),nitrogen as the carrier gas,column temperature at 130℃,and FID as the detector.Results Synthetic borneol(borneol and isoborneol) and naphetalene were separated well under the chromatographic condition.The average recovery of synthetic borneol was 96.58%.Conclusion The method is sensitive,accurate,and can be used to control the quality of the preparation.

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Available abstract

Objective To establish the determination for synthetic borneol in Naotong Injection by GC.Methods The internal standard method was employed.Naphthalene,the internal standard,was added to the sample before treatment.The GC system consisted of DB-WAX column(30 m×0.32 mm,0.25 μm),nitrogen as the carrier gas,column temperature at 130℃,and FID as the detector.Results Synthetic borneol(borneol and isoborneol) and naphetalene were separated well under the chromatographic condition.The average recovery of synthetic borneol was 96.58%.Conclusion The method is sensitive,accurate,and can be used to control the quality of the preparation.

Key concepts: Borneol, Chromatography, Gas chromatography, Chemistry, Wax, Internal standard, Naphthalene, Analytical Chemistry (journal)

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