Effects of curettage on the clinical outcomes of in vitro fertilization and embryo transfer of irregular echo endometrium

Objective To explore the effect of curettage on the clinical outcomes of irregular echo endometrium of natural cycle late follicular phase in IVF-ET cycles.Methods Before IVF-ET cycle , endometrial thickness were monitored by transvaginal ultrasound , which were performed in late follicular phase in all patients.There were 77patients with abnormal endometrial echoes in late follicular phase of natural cycle.All the patients were divided into observation group (n=47) and control group (n=30) randomly.Curettage was performed on day 1～2of menstrual cycle in IVF-ET cycle in the observation group , while it was not performed in the control group.The clinical outcomes and endometrial thickness and morphologic pattern were compared between the two groups.Results The rates of embryo implantation , clinical pregnancy in the observation group were 30.30 % and 53.19% , which were significantly higher than those in the control group (15.15%and 30%) .Endometrial echogenic pattern was ameliorated in late follicular phase in 85.11% of patients in observation group.Conclusion Curettage could not only significantly ameliorate the echogenic pattern of endometrium , but also improve the implantation and clinical pregnancy rates of IVF-ET.