Application of endometrial scraping in embryo transfer cycle

Objective To analyze the effect of endometrial scraping in embryo transfer cycle on clinical pregnancy rate. Methods The data of 1879 patients in embryo transfer cycles underwent in vitro fertlization-embryo transfer(IVF-ET) were retrospective analyzed.All patients underwent ultrasound examination before ovulation induction.They were divided into normal endometrium group and abnormal endometrium group according to endometrium echo and thickness.Patients with abnormal endometrium underwent endometrial scraping.Clinical pregnancy rates were compared between normal endometrium group and abnormal endometrium group,between underwent endometrial scraping group and control group. Results Female age was significant younger in normal endometrium group than that in abnormal endometrium group(30.56 and 32.77,P0.005).The clinical pregnancy rate in normal endometrium group was 49.26% and that in abnormal endometrium group was 41.87%,which was statistically significant(P0.05).In patients with abnormal endometrium who underwent endometrial scraping,female age was also significantly higher in abnormal endometrium group(33.11 and 31.41,P0.005),and the clinical pregnancy rate has no significant difference in two group(53.72% and 50.06%,P0.05). Conclusion(1).Endometrial abnormal echo rate increases along with female age rising.(2).Endometrial scraping in embryo transfer cycle can improve the clinical pregnancy rate.