2003•Yanke xinjinzhanRequires access

Application of mitomycin C in laser lacryocystoplasty

LV Hong, Qiang Lü

Abstract

ObjectiveTo evaluate the effects of mitomycin C(MMC) in laser lacryocystoplasty.MethodsSixty patients(71 eyes) with obstruction of lacrimal passage were randomly divided into MMC group and control group.In MMC group, 29 cases (35 eyes) firstly applied 0.25g·L -1 MMC for 5 minutes and then filled up TobraDex ointment. In control group, 31 cases (36 eyes) didn't apply MMC. All patients were followed up for 3~15 months. ResultsThe success rate of operation was 88.6% in MMC group and 69 4% in control group (P0.05).ConclusionMMC (0 25g·L -1) can effectively inhibit the scar formation, thus providing a higher successful rate of laser lacryocystoplasty.

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Key concepts: Mitomycin C, Surgery, Medicine, Laser, Ophthalmology, Optics, Physics