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Changes of the Function of Platelet and Anticoagulation in Patients with Acute Pancreatitis

Men Jianlon, XU Fenghu, Liu Wenlai

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Abstract

To investigate the clinical value of changes of platelet and anticoagulation function in patients with acute pancreatitis. Methods:β-TG,PF4 .TXB2 ,GMP-140,antithrombin-III,and protein C were measured in all patients. Results: There was no significant difference in all parameters between acute edema pancreatitis group and normal group(P0.05). Compared with the control group, parameters of platelet significantly increased in acute necrosis pancreatitis group(P 0.01), and parameters of anticoagulation significantly decreased (P 0.01). Conclusion: The platelet system was activated and the level of anticoagulation system decreased in acute necrosis pancreatitis. Parameters are important in understanding and preventing this disease.

About this research paper

What this paper is about

To investigate the clinical value of changes of platelet and anticoagulation function in patients with acute pancreatitis. Methods:β-TG,PF4 .TXB2 ,GMP-140,antithrombin-III,and protein C were measured in all patients. Results: There was no significant difference in all parameters between acute edema pancreatitis group and normal group(P0.05). Compared with the control group, parameters of platelet significantly increased in acute necrosis pancreatitis group(P 0.01), and parameters of anticoagulation significantly decreased (P 0.01). Conclusion: The platelet system was activated and the level of anticoagulation system decreased in acute necrosis pancreatitis. Parameters are important in understanding and preventing this disease.

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Available abstract

To investigate the clinical value of changes of platelet and anticoagulation function in patients with acute pancreatitis. Methods:β-TG,PF4 .TXB2 ,GMP-140,antithrombin-III,and protein C were measured in all patients. Results: There was no significant difference in all parameters between acute edema pancreatitis group and normal group(P0.05). Compared with the control group, parameters of platelet significantly increased in acute necrosis pancreatitis group(P 0.01), and parameters of anticoagulation significantly decreased (P 0.01). Conclusion: The platelet system was activated and the level of anticoagulation system decreased in acute necrosis pancreatitis. Parameters are important in understanding and preventing this disease.

Key concepts: Acute pancreatitis, Medicine, Pancreatitis, Platelet, Internal medicine, Gastroenterology, Antithrombin, Heparin

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