Plasma Adiponectin Level in Male With Obesity and Its Affecting Factors

To investigate the correlation between of plasma adiponectin and other parameters by detecting plasma adiponectin levels in male with or without obesity.96 male subjects were enrolled in the group,among them 40 male subjects with BMI≥25kg/m2.Fasting plasma adiponectin level were measured in each patient.The adiponectin level in male subjects with obesity [(7.48±3.4)μg/ml]were significantly lower than that in normal subjects [(10.57±4.73)μg/ml,P0.01).Multiple linear related analysis showed significantly negatively correlations between plasma adiponectin and WC(waist circumference),BMI(body mass index),BP(blood pressure),TC(total cholesterol),FINS(fasting blood insulin),HOMA-IR(the insulin resistance index was calculated according to the typical HOMA mode l) and positi vely correlation between plasma adiponectin and HDL-C(high-density lipoprotein-cholesterol) levels.WC,BMI,HOMA-IR were the most independent factors that affecting the level of plasma adiponectin.The plasma adiponectin levels were lower in male with obesity.Adiponectin may be intinmately related to obesity and insulin resistance.