Application Value Analysis of Detecting Serum Procalcitonin Levels in Sepsis Children

Objective: To explore the clinical significance of detecting the serum procalcitonin(PCT) level in children with sepsis.Methods: The serum PCT levels,C-reactive protein(CRP) levels and white blood cell(WBC) count were detected in 38 patients(16 chil-dren with severe sepsis,22 children with non-severe sepsis),and compared with 40 children without sepsis.Results: The serum PCT lev-els,CRP and WBC count in the sepsis group were significantly higher than non-sepsis group,the difference was statistically significant(P0.05).The sensitivity of PCT,CRP in the diagnosis of sepsis wasn't statistically significant(P0.05),but it was significantly higher than WBC count,the difference was statistically significant(P0.05).The specificity,positive predictive value,negative predictive value,Youden index of PCT were significantly higher than CRP and WBC count,the difference was statistically significant(P0.05);The serum PCT level in the severe sepsis group was significantly higher than that non-severe sepsis group,the difference was statistically signifi-cant(P0.05),but the serum levels of CRP and WBC count had no significant difference between the two groups(P0.05).Conclusions: PCT could be used as a sensitive serum marker in diagnosing sepsis in children.The effect of PCT is superior to CRP and WBC count.