The Value studies of serum Procalcttonin,Interleukin-6,C-reactive,and White Blood Cell Combined Detecting in Diagnosis of Children with Sepsis

OBJECTIVE To explore the values of serum Procalcitonin( PCT),Interleukin-6( IL-6). C-reactive protein( CRP) levels and White blood cell( WBC) count for diagnosis of children with sepsis. METHODS 89 of children who entered into PICU treatment. were divided into two groups: Sepsis group and Non-sepsis group. According to the diagnostic criteria of ACCP / SCM Conference,The PCT,IL-6,CRP and WBC level of the two groups were determined and compared with each other. RESULTS Compared to Non-sepsis group,Serum Procalcitonin,Interleukin-6,C-reactive protein levels of Sepsis group had significant difference( P 0. 05),and it was not significant difference of white blood cell levels. The specificity Sensitivity,Accuracy,Positive predictive value and Negative predictive value of PCT were higher than other projects. CONCLUSION WBC count was not be the diagnostic indicators of sepsis in children. Compared with WBC count,CRP and IL-6,PCT may reflect the most sensitive indicators of sepsis in children,PCT and IL-6 can be used as clinical assessment of sepsis in Children.