Association of high-sensitivity C-reaction protein with prehypertension

Objective To observe the changes of serum high-sensitivity C-reactive protein(Hs-CRP) level in patients with prehypertension and to investigate the relationship between inflammation and prehypertension. Meantime,some relative factors which aggravate inflammation were analyzed. Methods Total cholesterol(TC),triglyceride(TG), fasting blood glucose (FBG) and body mass index(BMI) were measured in 87 patients with prehypertension and 70 normal controls. Serum high sensitivity C-reactive protein Concentration was measured by applaying enzyme linked immunosorbent assay(ELISA). Results The Hs-CRP level of SBP 120-139 mm Hg prehypertension patients were significantly higher than those of normal controls group(P0.05).The Hs-CRP levels were significant Positively correlated to the levels of TC,FBG,TG and BMI(All P0.05). Conclusion The serum Hs-CRP level are increased obviously in the patient with prehypertension,prehypertension has an inflammation reaction .The elevated levels of TC,TG,FBG, and BMI all aggravate inflammation.