ScholarLens Back to search
2010•Zhongguo yaofangRequires access

Comparison of Clinical Efficacy of Amiodarone and Cedilanid in the Treatment of Paroxysmal Atrial Fibrillation with Intravenous Administration

Zhang Hou-min

Open publisher page 0 citations

Abstract

OBJECTIVE:To compare amiodarone and cedilanid in the treatment of paroxysmal atrial fibrillation(AF) with intravenous administration and control of heart rate.METHODS:47 AF patients were randomly given 150～600 mg amiodarone(amiodarone group,n=24) and 0.2～0.6 mg cedilanid(cedilanid group,n=23) intravenously.The outcome,change of heart rate and adverse drug reaction of 2 groups were observed.RESULTS:Effective rate of amiodarone group was significantly higher than that of cedilanid groups(P0.01).There were statistical significance in difference of heart rate before and after treatment(P0.01).Clinical efficacy of amiodarone group was superior to cedilanid groups.There were signigicant difference between 2 groups(P0.01).CONCLUSION:Amiodarone is more effective than cedilanid in decreasing heart rate with less ADR.Amiodarone is safe and effective in the treatment of PAF.

About this research paper

What this paper is about

OBJECTIVE:To compare amiodarone and cedilanid in the treatment of paroxysmal atrial fibrillation(AF) with intravenous administration and control of heart rate.METHODS:47 AF patients were randomly given 150～600 mg amiodarone(amiodarone group,n=24) and 0.2～0.6 mg cedilanid(cedilanid group,n=23) intravenously.The outcome,change of heart rate and adverse drug reaction of 2 groups were observed.RESULTS:Effective rate of amiodarone group was significantly higher than that of cedilanid groups(P0.01).There were statistical significance in difference of heart rate before and after treatment(P0.01).Clinical efficacy of amiodarone group was superior to cedilanid groups.There were signigicant difference between 2 groups(P0.01).CONCLUSION:Amiodarone is more effective than cedilanid in decreasing heart rate with less ADR.Amiodarone is safe and effective in the treatment of PAF.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE:To compare amiodarone and cedilanid in the treatment of paroxysmal atrial fibrillation(AF) with intravenous administration and control of heart rate.METHODS:47 AF patients were randomly given 150～600 mg amiodarone(amiodarone group,n=24) and 0.2～0.6 mg cedilanid(cedilanid group,n=23) intravenously.The outcome,change of heart rate and adverse drug reaction of 2 groups were observed.RESULTS:Effective rate of amiodarone group was significantly higher than that of cedilanid groups(P0.01).There were statistical significance in difference of heart rate before and after treatment(P0.01).Clinical efficacy of amiodarone group was superior to cedilanid groups.There were signigicant difference between 2 groups(P0.01).CONCLUSION:Amiodarone is more effective than cedilanid in decreasing heart rate with less ADR.Amiodarone is safe and effective in the treatment of PAF.

Key concepts: Amiodarone, Medicine, Atrial fibrillation, Clinical efficacy, Cardiology, Internal medicine, Anesthesia, Statistical significance

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Comparison of Clinical Efficacy of Amiodarone and Cedilanid in the Treatment of Paroxysmal Atrial Fibrillation with Intravenous Administration — Research Paper | ScholarLens