Analysis of clindamycin resistance and common antibiotic resistance in Staphylococcus epidermidis

Objective To Separate the Staphylococcus epidermidis from clinical samples at first,then test their resistance to commonly used antibiotics and analyze the occurrence rate of inducible resistance of Erythromycin to Clindamycin.Methods Staphylococcus epidermidis were seperated from cultivited clinical samples and their inducible resistance of Erythromycin to Clindamycin was checked by K-B method.The percentage of Erythromycin inducible Clindamycin resistance was checked by the D-test and MRSE was detected by XiDing cephalosporins method.Results Within 86 strains of Staphylococcus epidermidis,MRSE were 72 plants,taking 83.72%,and 14 plants of MSSE accounted for 16.28%.34 strains of D test positive strains(taking 39.53%)and 52 strains of D test negative strains(taking 60.47%) were checked from total D test strains.Among all the Staphylococcus strains,their resistance rate respectively are:Penicillin with100%,Erythromycin with 88.37%,and Clindamycin with 24.42%.Linezolid and vancomycin are both 100% sensible to all the seperated Staphylococcus strains.Conclusion The resistance rate of Penicillin、Erythromyci and Clindamycin are all high.Conventional D-test can make a good help to making good use of Macrolide Antibiotics and Clindamycins.