Analysis on the Distribution and Drug Resistance of the Pathogenic Bacteria Causing Lower Respiratory Tract Infection in Senile Patients in a Hospital in Beijing

Objective To analyze the distribution and drug resistance of pathogenic bacteria in senile patients with lower respiratory tract infection,and provide a reasonable basis of prevention and treatment for the clinic. Methods The culture and drug sensitive test results of pathogenic bacteria separated from 438 sputum samples from senile patients with lower respiratory tract infection in Department of Respiratory Medicine from February 2012 to November 2013 were retrospectively analyzed. Results There were 392 strains separated from 438 samples. Among the 392 strains,226 strains( 57. 7%) were gram-negative,mainly including klebsiella pneumoniae,escherichia coli,pseudomonas aeruginosa and Bauman acinetobacter.While 125 strains( 31. 9%) were gram-positive,which mainly contained staphylococcus aureus,staphylococcus haemolyticus and staphylococcus epidermidis. Forty-one strains( 10. 5%) were fungi,and candida albicans was the most. Drug sensitive test results showed that klebsiella pneumoniae and escherichia coli had lowest resistance to imipenem,Bauman acinetobacter had lower resistance rates to sulbactam and cefoperazone and imipenem,and pseudomonas had the lowest resistance rate to amikacin. Staphylococcus aureus,staphylococcus haemolyticus and staphylococcus epidermidis were all sensitive to vancomycin and teicoplanin. Conclusion Gram-negative bacterium is the major pathogenic bacteria in geriatric patients with lower respiratory tract infection. The situation of bacterial drug resistance is serious,and we should choose rational antibacterials according to drug sensitive test.