Preparation and quality control of ornidazole suppository
Duan Yanhua
Abstract
Duan Yanhua
Abstract
Objective To prepare ornidazole suppository and establish the quality standard for the treatment of periodontitis.Methods The proper base material was chosen and the proportion of main ingredients was determined.The content of ornidazole in the ornidazole suppository was detected by ultraviolet spectrophotometry.Results For the suppository prepared by ornidazole and gelatin glycerol,the recovery rate was 100.1%,RSD was 0.3%.Conclusion The preparation technique is simple,stable in quality,and convenient,accurate and precise in quality control.It is possible to supply a new therapy to periodontitis.
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Objective To prepare ornidazole suppository and establish the quality standard for the treatment of periodontitis.Methods The proper base material was chosen and the proportion of main ingredients was determined.The content of ornidazole in the ornidazole suppository was detected by ultraviolet spectrophotometry.Results For the suppository prepared by ornidazole and gelatin glycerol,the recovery rate was 100.1%,RSD was 0.3%.Conclusion The preparation technique is simple,stable in quality,and convenient,accurate and precise in quality control.It is possible to supply a new therapy to periodontitis.
Key concepts: Ornidazole, Suppository, Chromatography, Infrared Spectrophotometry, Chemistry, Medicine, Pharmacology