2006•Di-san junyi daxue xuebaoRequires access

Preparation and quality control of ornidazole suppository

Duan Yanhua

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Abstract

Objective To prepare ornidazole suppository and establish the quality standard for the treatment of periodontitis.Methods The proper base material was chosen and the proportion of main ingredients was determined.The content of ornidazole in the ornidazole suppository was detected by ultraviolet spectrophotometry.Results For the suppository prepared by ornidazole and gelatin glycerol,the recovery rate was 100.1%,RSD was 0.3%.Conclusion The preparation technique is simple,stable in quality,and convenient,accurate and precise in quality control.It is possible to supply a new therapy to periodontitis.

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What this paper is about

Objective To prepare ornidazole suppository and establish the quality standard for the treatment of periodontitis.Methods The proper base material was chosen and the proportion of main ingredients was determined.The content of ornidazole in the ornidazole suppository was detected by ultraviolet spectrophotometry.Results For the suppository prepared by ornidazole and gelatin glycerol,the recovery rate was 100.1%,RSD was 0.3%.Conclusion The preparation technique is simple,stable in quality,and convenient,accurate and precise in quality control.It is possible to supply a new therapy to periodontitis.

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Available abstract

Objective To prepare ornidazole suppository and establish the quality standard for the treatment of periodontitis.Methods The proper base material was chosen and the proportion of main ingredients was determined.The content of ornidazole in the ornidazole suppository was detected by ultraviolet spectrophotometry.Results For the suppository prepared by ornidazole and gelatin glycerol,the recovery rate was 100.1%,RSD was 0.3%.Conclusion The preparation technique is simple,stable in quality,and convenient,accurate and precise in quality control.It is possible to supply a new therapy to periodontitis.

Key concepts: Ornidazole, Suppository, Chromatography, Infrared Spectrophotometry, Chemistry, Medicine, Pharmacology

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