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2009•Zhongguo shiyong neike zazhiRequires access

The clinical value of serum CA125 in Non-Hodgkin's lymphoma.

Meiyu Fang

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Abstract

Objective To investigate the level of serum CA125 in patients with non-Hodgkin's lymphoma(NHL) and its clinical value.Methods All the data of this study was collected from the first affiliated hospital of China Medical University,during September 2004 to March 2006.Serum CA125 levels were measured in 42 patients with NHL.The association with gender,clinical stages,B symptoms,effusions,International Prognostic Score(IPI),serum LDH(lactate dehydrogenase),beta 2 microglobulin(β2-MG) levels and response to treatment was evaluated.Results High level of CA125 was found to be obviously correlated with B symptoms,effusions,IPI score,serum LDH(P0.05),and it may also be associated with the progression of disease.Conclusion Serum CA125 measurement is of value in diagnosis,monitering and assessing prognosis in patients with NHL.

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What this paper is about

Objective To investigate the level of serum CA125 in patients with non-Hodgkin's lymphoma(NHL) and its clinical value.Methods All the data of this study was collected from the first affiliated hospital of China Medical University,during September 2004 to March 2006.Serum CA125 levels were measured in 42 patients with NHL.The association with gender,clinical stages,B symptoms,effusions,International Prognostic Score(IPI),serum LDH(lactate dehydrogenase),beta 2 microglobulin(β2-MG) levels and response to treatment was evaluated.Results High level of CA125 was found to be obviously correlated with B symptoms,effusions,IPI score,serum LDH(P0.05),and it may also be associated with the progression of disease.Conclusion Serum CA125 measurement is of value in diagnosis,monitering and assessing prognosis in patients with NHL.

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Available abstract

Objective To investigate the level of serum CA125 in patients with non-Hodgkin's lymphoma(NHL) and its clinical value.Methods All the data of this study was collected from the first affiliated hospital of China Medical University,during September 2004 to March 2006.Serum CA125 levels were measured in 42 patients with NHL.The association with gender,clinical stages,B symptoms,effusions,International Prognostic Score(IPI),serum LDH(lactate dehydrogenase),beta 2 microglobulin(β2-MG) levels and response to treatment was evaluated.Results High level of CA125 was found to be obviously correlated with B symptoms,effusions,IPI score,serum LDH(P0.05),and it may also be associated with the progression of disease.Conclusion Serum CA125 measurement is of value in diagnosis,monitering and assessing prognosis in patients with NHL.

Key concepts: Medicine, Beta-2 microglobulin, Internal medicine, Lactate dehydrogenase, Lymphoma, Gastroenterology, Hodgkin lymphoma, Disease

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