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2013•Chinese Journal of New Clinical MedicineRequires access

The determination of serum LDH and β_2-MG in patients with non-Hodgkin's lymphoma and its clinical significance

Yong Wang

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Abstract

Objective To study the relationship between the serum level of LDH,β2-MG and clinical diagnosis,stage and effectiveness of treatment in patients with non-Hodgkin lymphoma(NHL).Methods The level of serum LDH and β2-MG in 32 patients with NHL(NHL group) and 35 healthy subjects(control group)were detected respectively.Results(1)The level of serum LDH and β2-MG in NHL group were obviously higher than those in the control group(P0.01);(2)The level of serum LDH and β2-MG in Ⅲ+Ⅳstage were obviously higher than that in Ⅰ+Ⅱ stage(P0.01);(3) After two cycles of chemotherapy,there was statistical difference between prechemotherapy and postchemotherapy(P0.01).Conclusion The levels of serum LDH and β2-MG can be taked as an reference index for diagnosis,classification,effectiveness of treatment in the patients with NHL.

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What this paper is about

Objective To study the relationship between the serum level of LDH,β2-MG and clinical diagnosis,stage and effectiveness of treatment in patients with non-Hodgkin lymphoma(NHL).Methods The level of serum LDH and β2-MG in 32 patients with NHL(NHL group) and 35 healthy subjects(control group)were detected respectively.Results(1)The level of serum LDH and β2-MG in NHL group were obviously higher than those in the control group(P0.01);(2)The level of serum LDH and β2-MG in Ⅲ+Ⅳstage were obviously higher than that in Ⅰ+Ⅱ stage(P0.01);(3) After two cycles of chemotherapy,there was statistical difference between prechemotherapy and postchemotherapy(P0.01).Conclusion The levels of serum LDH and β2-MG can be taked as an reference index for diagnosis,classification,effectiveness of treatment in the patients with NHL.

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Available abstract

Objective To study the relationship between the serum level of LDH,β2-MG and clinical diagnosis,stage and effectiveness of treatment in patients with non-Hodgkin lymphoma(NHL).Methods The level of serum LDH and β2-MG in 32 patients with NHL(NHL group) and 35 healthy subjects(control group)were detected respectively.Results(1)The level of serum LDH and β2-MG in NHL group were obviously higher than those in the control group(P0.01);(2)The level of serum LDH and β2-MG in Ⅲ+Ⅳstage were obviously higher than that in Ⅰ+Ⅱ stage(P0.01);(3) After two cycles of chemotherapy,there was statistical difference between prechemotherapy and postchemotherapy(P0.01).Conclusion The levels of serum LDH and β2-MG can be taked as an reference index for diagnosis,classification,effectiveness of treatment in the patients with NHL.

Key concepts: Medicine, Lymphoma, Internal medicine, Stage (stratigraphy), Gastroenterology, Clinical significance, Non-Hodgkin's lymphoma, Hodgkin lymphoma

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