The Clinical Observation of Irbesartan and Amiodarone in the Treatment of Patients with Congestive Heart Failure Accompanied with Ventricular Arrhythmia

Objective To observe the efficacy of Irbesartan and amiodarone in the treatment of patients with congestive heart failure and ventricular arrhythmia. Methods 40 patients with congestive heart failure and ventricular arrhythmia admitted in our hospital from January, 2011 to January, 2012 were divided into observation group and control group with 20 patients in each group. The two groups of patients were given cardiac stimulants, diuretics, β-blockers and vasodilators. At the same time, amiodarone was given to them, 200 mg, 3 times a day orally, 1 week later changed to 2 times a day, 2 weeks later to 1 time a day, and gradually reduced to maintenance dose. Based on the above, the observation group was given irbesartan 80 mg/d orally in addition, and added to 160 mg/d if the patients had no discomfort. Results After treatment, the efficacy of the cardiac function of the observation group and the efficacy of patients with ventricular arrhythmias in the observation group were significantly better than those of the control group, the differences between the two groups were statistically significant (P0.05). Conclusion Irbesartan combined with amiodarone in treatment of congestive heart failure accompanied with ventricular arrhythmia can improve the clinical efficacy with good safety, which is worthy of promotion and application.