Application of insulin pump in the treatment of newly diagnosed type 2 diabetes mellitus

Objective To observe the therapeutic effect of treating newly diagnosed type 2 diabetes mellitus with aspart insulin continuous subcutaneous infusion and aspart insulin 30 subcutaneous injection. Methods 50 patients with type 2 DM were randomly divided into group A and group B,patients in group A were treated with aspart insulin continuous subcutaneous infusion. And patients in group B received aspart insulin 30 subcutaneous injection twice per day at morning and evening,and adjust drug dose according to the level of blood glucose. The levels of fasting plasma glucose( FPG),2 hours postprandial glucose( 2h PG),therapeutic time, insulin dose and the level of hypoglycemia were compared between the two groups. Results CSII and aspart 30 could decrease blood glucose efficiently( P 0. 01),the differences of fasting plasma glucose( FPG) levels between the two groups was no statistically significant( P 0. 05),but 2 hours postprandial glucose( 2h PG) in aspart CSII group was lower than that of aspart 30 group( P 0. 05). It cost more time before hypoglycemia occurred in CSII group( P 0. 01). Conclusions Aspart insulin continuous subcutaneous infusion is effective and safe in the treatment of newly diagnosed type 2 diabetes mellitus.