Study on Tanshinone Extracted from Salvia miltiorrhiza Bge. Dregs

[Objective] The aim was to extract tanshinone from Salvia miltiorrhiza Bge. dregs and determine tanshinone components. [Method] Organic solvent method was adopted to extract tanshinone from S. miltiorrhiza dregs and TLC was used to determine the optimum extraction solvent. The components of tanshinone was measured with HPLC. [Result] Ether was the best solvent to extract tanshinone from S. miltiorrhiza dregs. After water immersion,dry dregs of S. miltiorrhiza and Panax notoginseng were extracted with ethanol to obtain fat-soluble extracts. Then with ether as the solvent for soxhlet extraction,the yield of crude tanshinone was 2.17%. The HPLC detection showed that the contents of tanshinone ⅡA,methylenetanshinone,cryptotanshinone,tanshinone I were 3.62%,1.02%,2.56%,2.75% respectively. [Conclusion] The components of tanshinone in S. miltiorrhiza dregs were basically the same as tanshinone in medicine S. miltiorrhiza. S. miltiorrhiza dregs could be used as a kind of tanshinone resource,which has the value of development and utilization.